Difference between revisions of "YBR192W"

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'''Description of YBR192W:''' Mitochondrial pyrimidine nucleotide transporter; imports pyrimidine nucleoside triphosphates and exports pyrimidine nucleoside monophosphates; member of the mitochondrial carrier family<ref name='S000045513'>Van Dyck E, et al. (1995) Overexpression of a novel member of the mitochondrial carrier family rescues defects in both DNA and RNA metabolism in yeast mitochondria. Mol Gen Genet 246(4):426-36 {{SGDpaper|S000045513}} PMID 7891656</ref><ref name='S000061149'>el Moualij B, et al. (1997) Phylogenetic classification of the mitochondrial carrier family of Saccharomyces cerevisiae. Yeast 13(6):573-81 {{SGDpaper|S000061149}} PMID 9178508</ref><ref name='S000086806'>Marobbio CM, et al. (2006) Identification of a mitochondrial transporter for pyrimidine nucleotides in Saccharomyces cerevisiae: bacterial expression, reconstitution and functional characterization. Biochem J 393(Pt 2):441-6
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'''Description of YBR192W:''' Mitochondrial pyrimidine nucleotide transporter; imports pyrimidine nucleoside triphosphates and exports pyrimidine nucleoside monophosphates; member of the mitochondrial carrier family<ref name='S000086806'>Marobbio CM, et al. (2006) Identification of a mitochondrial transporter for pyrimidine nucleotides in Saccharomyces cerevisiae: bacterial expression, reconstitution and functional characterization. Biochem J 393(Pt 2):441-6 {{SGDpaper|S000086806}} PMID 16194150</ref><ref name='S000045513'>Van Dyck E, et al. (1995) Overexpression of a novel member of the mitochondrial carrier family rescues defects in both DNA and RNA metabolism in yeast mitochondria. Mol Gen Genet 246(4):426-36 {{SGDpaper|S000045513}} PMID 7891656</ref><ref name='S000061149'>el Moualij B, et al. (1997) Phylogenetic classification of the mitochondrial carrier family of Saccharomyces cerevisiae. Yeast 13(6):573-81
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{{SGDpaper|S000061149}} PMID 9178508</ref>
 
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Revision as of 14:05, 25 February 2010

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Systematic name YBR192W
Gene name RIM2
Aliases PYT1
Feature type ORF, Verified
Coordinates Chr II:607647..608780
Primary SGDID S000000396


Description of YBR192W: Mitochondrial pyrimidine nucleotide transporter; imports pyrimidine nucleoside triphosphates and exports pyrimidine nucleoside monophosphates; member of the mitochondrial carrier family[1][2][3]




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Community Commentary

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Protein Details

Protein Function/Process

Rim2p has been identified as a yeast mitochondrial pyrimidine nucleotide transporter. It transported the pyrimidine (deoxy)nucleoside tri- and diphosphates and, to a lesser extent, pyrimidine (deoxy)nucleoside monophosphates by a counter-exchange mechanism. [1] [4]





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References

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  1. 1.0 1.1 Marobbio CM, et al. (2006) Identification of a mitochondrial transporter for pyrimidine nucleotides in Saccharomyces cerevisiae: bacterial expression, reconstitution and functional characterization. Biochem J 393(Pt 2):441-6 SGD PMID 16194150
  2. Van Dyck E, et al. (1995) Overexpression of a novel member of the mitochondrial carrier family rescues defects in both DNA and RNA metabolism in yeast mitochondria. Mol Gen Genet 246(4):426-36 SGD PMID 7891656
  3. el Moualij B, et al. (1997) Phylogenetic classification of the mitochondrial carrier family of Saccharomyces cerevisiae. Yeast 13(6):573-81 SGD PMID 9178508
  4. submitted by Carlo M. T. Marobbio on 2005-10-17

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