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Systematic name YBR192W
Gene name RIM2
Aliases PYT1
Feature type ORF, Verified
Coordinates Chr II:607652..608785
Primary SGDID S000000396

Description of YBR192W: Mitochondrial pyrimidine nucleotide transporter; imports pyrimidine nucleoside triphosphates and exports pyrimidine nucleoside monophosphates; member of the mitochondrial carrier family[1][2][3]


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Protein Details

Protein Function/Process

Rim2p has been identified as a yeast mitochondrial pyrimidine nucleotide transporter. It transported the pyrimidine (deoxy)nucleoside tri- and diphosphates and, to a lesser extent, pyrimidine (deoxy)nucleoside monophosphates by a counter-exchange mechanism. [1] [4]



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  1. 1.0 1.1 Marobbio CM, et al. (2006) Identification of a mitochondrial transporter for pyrimidine nucleotides in Saccharomyces cerevisiae: bacterial expression, reconstitution and functional characterization. Biochem J 393(Pt 2):441-6 SGD PMID 16194150
  2. Van Dyck E, et al. (1995) Overexpression of a novel member of the mitochondrial carrier family rescues defects in both DNA and RNA metabolism in yeast mitochondria. Mol Gen Genet 246(4):426-36 SGD PMID 7891656
  3. el Moualij B, et al. (1997) Phylogenetic classification of the mitochondrial carrier family of Saccharomyces cerevisiae. Yeast 13(6):573-81 SGD PMID 9178508
  4. submitted by Carlo M. T. Marobbio on 2005-10-17

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