Difference between revisions of "YBR135W"
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| − | '''Description of YBR135W:''' Cyclin-dependent protein kinase regulatory subunit and adaptor; modulates proteolysis of M-phase targets through interactions with the proteasome; role in transcriptional regulation, recruiting proteasomal subunits to target gene promoters<ref name=' | + | '''Description of YBR135W:''' Cyclin-dependent protein kinase regulatory subunit and adaptor; modulates proteolysis of M-phase targets through interactions with the proteasome; role in transcriptional regulation, recruiting proteasomal subunits to target gene promoters<ref name='S000039561'>Hadwiger JA, et al. (1989) The Saccharomyces cerevisiae CKS1 gene, a homolog of the Schizosaccharomyces pombe suc1+ gene, encodes a subunit of the Cdc28 protein kinase complex. Mol Cell Biol 9(5):2034-41 {{SGDpaper|S000039561}} PMID 2664468</ref><ref name='S000054457'>Kaiser P, et al. (1999) Cyclin-dependent kinase and Cks/Suc1 interact with the proteasome in yeast to control proteolysis of M-phase targets. Genes Dev 13(9):1190-202 {{SGDpaper|S000054457}} PMID 10323869</ref><ref name='S000062128'>Reynard GJ, et al. (2000) Cks1 is required for G(1) cyclin-cyclin-dependent kinase activity in budding yeast. Mol Cell Biol 20(16):5858-64 {{SGDpaper|S000062128}} PMID 10913169</ref><ref name='S000073499'>Morris MC, et al. (2003) Cks1-dependent proteasome recruitment and activation of CDC20 transcription in budding yeast. Nature 423(6943):1009-13 |
| − | {{SGDpaper| | + | {{SGDpaper|S000073499}} PMID 12827207</ref> |
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Revision as of 14:05, 31 March 2009
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| Systematic name | YBR135W |
| Gene name | CKS1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr II:504848..505300 |
| Primary SGDID | S000000339 |
Description of YBR135W: Cyclin-dependent protein kinase regulatory subunit and adaptor; modulates proteolysis of M-phase targets through interactions with the proteasome; role in transcriptional regulation, recruiting proteasomal subunits to target gene promoters[1][2][3][4]
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References
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- ↑ Hadwiger JA, et al. (1989) The Saccharomyces cerevisiae CKS1 gene, a homolog of the Schizosaccharomyces pombe suc1+ gene, encodes a subunit of the Cdc28 protein kinase complex. Mol Cell Biol 9(5):2034-41 SGD PMID 2664468
- ↑ Kaiser P, et al. (1999) Cyclin-dependent kinase and Cks/Suc1 interact with the proteasome in yeast to control proteolysis of M-phase targets. Genes Dev 13(9):1190-202 SGD PMID 10323869
- ↑ Reynard GJ, et al. (2000) Cks1 is required for G(1) cyclin-cyclin-dependent kinase activity in budding yeast. Mol Cell Biol 20(16):5858-64 SGD PMID 10913169
- ↑ Morris MC, et al. (2003) Cks1-dependent proteasome recruitment and activation of CDC20 transcription in budding yeast. Nature 423(6943):1009-13 SGD PMID 12827207
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