YBR135W
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| Systematic name | YBR135W |
| Gene name | CKS1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr II:504854..505306 |
| Primary SGDID | S000000339 |
Description of YBR135W: Cyclin-dependent protein kinase regulatory subunit and adaptor; modulates proteolysis of M-phase targets through interactions with the proteasome; role in transcriptional regulation, recruiting proteasomal subunits to target gene promoters[1][2][3][4]
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References
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- ↑ Hadwiger JA, et al. (1989) The Saccharomyces cerevisiae CKS1 gene, a homolog of the Schizosaccharomyces pombe suc1+ gene, encodes a subunit of the Cdc28 protein kinase complex. Mol Cell Biol 9(5):2034-41 SGD PMID 2664468
- ↑ Kaiser P, et al. (1999) Cyclin-dependent kinase and Cks/Suc1 interact with the proteasome in yeast to control proteolysis of M-phase targets. Genes Dev 13(9):1190-202 SGD PMID 10323869
- ↑ Morris MC, et al. (2003) Cks1-dependent proteasome recruitment and activation of CDC20 transcription in budding yeast. Nature 423(6943):1009-13 SGD PMID 12827207
- ↑ Reynard GJ, et al. (2000) Cks1 is required for G(1) cyclin-cyclin-dependent kinase activity in budding yeast. Mol Cell Biol 20(16):5858-64 SGD PMID 10913169
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