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Systematic name YBR058C
Gene name UBP14
Aliases GID6
Feature type ORF, Verified
Coordinates Chr II:356017..353672
Primary SGDID S000000262

Description of YBR058C: Ubiquitin-specific protease that specifically disassembles unanchored ubiquitin chains; involved in fructose-1,6-bisphosphatase (Fbp1p) degradation; similar to human isopeptidase T[1][2][3]


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See Help:References on how to add references

  1. Amerik AYu, et al. (1997) In vivo disassembly of free polyubiquitin chains by yeast Ubp14 modulates rates of protein degradation by the proteasome. EMBO J 16(16):4826-38 SGD PMID 9305625
  2. Hochstrasser M (1996) Ubiquitin-dependent protein degradation. Annu Rev Genet 30:405-39 SGD PMID 8982460
  3. Regelmann J, et al. (2003) Catabolite degradation of fructose-1,6-bisphosphatase in the yeast Saccharomyces cerevisiae: a genome-wide screen identifies eight novel GID genes and indicates the existence of two degradation pathways. Mol Biol Cell 14(4):1652-63 SGD PMID 12686616

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