YBR058C

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Systematic name YBR058C
Gene name UBP14
Aliases GID6
Feature type ORF, Verified
Coordinates Chr II:356017..353672
Primary SGDID S000000262


Description of YBR058C: Ubiquitin-specific protease that specifically disassembles unanchored ubiquitin chains; involved in fructose-1,6-bisphosphatase (Fbp1p) degradation; similar to human isopeptidase T[1][2][3]




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References

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  1. Amerik AYu, et al. (1997) In vivo disassembly of free polyubiquitin chains by yeast Ubp14 modulates rates of protein degradation by the proteasome. EMBO J 16(16):4826-38 SGD PMID 9305625
  2. Hochstrasser M (1996) Ubiquitin-dependent protein degradation. Annu Rev Genet 30:405-39 SGD PMID 8982460
  3. Regelmann J, et al. (2003) Catabolite degradation of fructose-1,6-bisphosphatase in the yeast Saccharomyces cerevisiae: a genome-wide screen identifies eight novel GID genes and indicates the existence of two degradation pathways. Mol Biol Cell 14(4):1652-63 SGD PMID 12686616

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