Difference between revisions of "YBR010W"
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| − | '''Description of YBR010W:''' Histone H3, core histone protein required for chromatin assembly, part of heterochromatin-mediated telomeric and HM silencing; one of two identical histone H3 proteins (see HHT2); regulated by acetylation, methylation, and phosphorylation<ref name=' | + | '''Description of YBR010W:''' Histone H3, core histone protein required for chromatin assembly, part of heterochromatin-mediated telomeric and HM silencing; one of two identical histone H3 proteins (see HHT2); regulated by acetylation, methylation, and phosphorylation<ref name='S000044144'>Zhang W, et al. (1998) Essential and redundant functions of histone acetylation revealed by mutation of target lysines and loss of the Gcn5p acetyltransferase. EMBO J 17(11):3155-67 {{SGDpaper|S000044144}} PMID 9606197</ref><ref name='S000046618'>Lo WS, et al. (2000) Phosphorylation of serine 10 in histone H3 is functionally linked in vitro and in vivo to Gcn5-mediated acetylation at lysine 14. Mol Cell 5(6):917-26 {{SGDpaper|S000046618}} PMID 10911986</ref><ref name='S000053597'>Hsu JY, et al. (2000) Mitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes. Cell 102(3):279-91 {{SGDpaper|S000053597}} PMID 10975519</ref><ref name='S000057267'>Smith MM and Andresson OS (1983) DNA sequences of yeast H3 and H4 histone genes from two non-allelic gene sets encode identical H3 and H4 proteins. J Mol Biol 169(3):663-90 {{SGDpaper|S000057267}} PMID 6355483</ref><ref name='S000071381'>van Leeuwen F, et al. (2002) Dot1p modulates silencing in yeast by methylation of the nucleosome core. Cell 109(6):745-56 {{SGDpaper|S000071381}} PMID 12086673</ref><ref name='S000072594'>Thompson JS, et al. (2003) Identification of a Functional Domain Within the Essential Core of Histone H3 That Is Required for Telomeric and HM Silencing in Saccharomyces cerevisiae. Genetics 163(1):447-52 {{SGDpaper|S000072594}} PMID 12586729</ref><ref name='S000073147'>Krogan NJ, et al. (2003) The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: linking transcriptional elongation to histone methylation. Mol Cell 11(3):721-9 {{SGDpaper|S000073147}} PMID 12667454</ref><ref name='S000073471'>Boa S, et al. (2003) Saccharomyces cerevisiae Set1p is a methyltransferase specific for lysine 4 of histone H3 and is required for efficient gene expression. Yeast 20(9):827-35 |
| − | {{SGDpaper| | + | {{SGDpaper|S000073471}} PMID 12845608</ref> |
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Revision as of 03:40, 18 December 2008
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| Systematic name | YBR010W |
| Gene name | HHT1 |
| Aliases | BUR5, SIN2 |
| Feature type | ORF, Verified |
| Coordinates | Chr II:256329..256739 |
| Primary SGDID | S000000214 |
Description of YBR010W: Histone H3, core histone protein required for chromatin assembly, part of heterochromatin-mediated telomeric and HM silencing; one of two identical histone H3 proteins (see HHT2); regulated by acetylation, methylation, and phosphorylation[1][2][3][4][5][6][7][8]
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References
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- ↑ Zhang W, et al. (1998) Essential and redundant functions of histone acetylation revealed by mutation of target lysines and loss of the Gcn5p acetyltransferase. EMBO J 17(11):3155-67 SGD PMID 9606197
- ↑ Lo WS, et al. (2000) Phosphorylation of serine 10 in histone H3 is functionally linked in vitro and in vivo to Gcn5-mediated acetylation at lysine 14. Mol Cell 5(6):917-26 SGD PMID 10911986
- ↑ Hsu JY, et al. (2000) Mitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes. Cell 102(3):279-91 SGD PMID 10975519
- ↑ Smith MM and Andresson OS (1983) DNA sequences of yeast H3 and H4 histone genes from two non-allelic gene sets encode identical H3 and H4 proteins. J Mol Biol 169(3):663-90 SGD PMID 6355483
- ↑ van Leeuwen F, et al. (2002) Dot1p modulates silencing in yeast by methylation of the nucleosome core. Cell 109(6):745-56 SGD PMID 12086673
- ↑ Thompson JS, et al. (2003) Identification of a Functional Domain Within the Essential Core of Histone H3 That Is Required for Telomeric and HM Silencing in Saccharomyces cerevisiae. Genetics 163(1):447-52 SGD PMID 12586729
- ↑ Krogan NJ, et al. (2003) The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: linking transcriptional elongation to histone methylation. Mol Cell 11(3):721-9 SGD PMID 12667454
- ↑ Boa S, et al. (2003) Saccharomyces cerevisiae Set1p is a methyltransferase specific for lysine 4 of histone H3 and is required for efficient gene expression. Yeast 20(9):827-35 SGD PMID 12845608
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