YBR010W

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Systematic name YBR010W
Gene name HHT1
Aliases BUR5, SIN2
Feature type ORF, Verified
Coordinates Chr II:256331..256741
Primary SGDID S000000214


Description of YBR010W: Histone H3, core histone protein required for chromatin assembly, part of heterochromatin-mediated telomeric and HM silencing; one of two identical histone H3 proteins (see HHT2); regulated by acetylation, methylation, and phosphorylation[1][2][3][4][5][6][7][8]




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References

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  1. Jump up Boa S, et al. (2003) Saccharomyces cerevisiae Set1p is a methyltransferase specific for lysine 4 of histone H3 and is required for efficient gene expression. Yeast 20(9):827-35 SGD PMID 12845608
  2. Jump up Hsu JY, et al. (2000) Mitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes. Cell 102(3):279-91 SGD PMID 10975519
  3. Jump up Krogan NJ, et al. (2003) The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: linking transcriptional elongation to histone methylation. Mol Cell 11(3):721-9 SGD PMID 12667454
  4. Jump up Lo WS, et al. (2000) Phosphorylation of serine 10 in histone H3 is functionally linked in vitro and in vivo to Gcn5-mediated acetylation at lysine 14. Mol Cell 5(6):917-26 SGD PMID 10911986
  5. Jump up Smith MM and Andresson OS (1983) DNA sequences of yeast H3 and H4 histone genes from two non-allelic gene sets encode identical H3 and H4 proteins. J Mol Biol 169(3):663-90 SGD PMID 6355483
  6. Jump up Thompson JS, et al. (2003) Identification of a Functional Domain Within the Essential Core of Histone H3 That Is Required for Telomeric and HM Silencing in Saccharomyces cerevisiae. Genetics 163(1):447-52 SGD PMID 12586729
  7. Jump up Zhang W, et al. (1998) Essential and redundant functions of histone acetylation revealed by mutation of target lysines and loss of the Gcn5p acetyltransferase. EMBO J 17(11):3155-67 SGD PMID 9606197
  8. Jump up van Leeuwen F, et al. (2002) Dot1p modulates silencing in yeast by methylation of the nucleosome core. Cell 109(6):745-56 SGD PMID 12086673

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