Difference between revisions of "YBL079W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000175 YBL079W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''NUP170 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''NUP170 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr II: | + | |nowrap| Chr II:75259..79767 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000000175 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000000175 | ||
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| − | '''Description of YBL079W:''' Subunit of the nuclear pore complex (NPC) | + | '''Description of YBL079W:''' Subunit of the inner ring of the nuclear pore complex (NPC); contributes to NPC assembly and nucleocytoplasmic transport; has similarity to Nup157p; both Nup170p and NUP157p are similar to human Nup155p<ref name='S000057786'>Aitchison JD, et al. (1995) Two novel related yeast nucleoporins Nup170p and Nup157p: complementation with the vertebrate homologue Nup155p and functional interactions with the yeast nuclear pore-membrane protein Pom152p. J Cell Biol 131(5):1133-48 {{SGDpaper|S000057786}} PMID 8522578</ref><ref name='S000135178'>Fernandez-Martinez J and Rout MP (2009) Nuclear pore complex biogenesis. Curr Opin Cell Biol 21(4):603-12 {{SGDpaper|S000135178}} PMID 19524430</ref><ref name='S000071853'>Iouk T, et al. (2002) The yeast nuclear pore complex functionally interacts with components of the spindle assembly checkpoint. J Cell Biol 159(5):807-19 {{SGDpaper|S000071853}} PMID 12473689</ref><ref name='S000046344'>Kenna MA, et al. (1996) Yeast N1e3p/Nup170p is required for normal stoichiometry of FG nucleoporins within the nuclear pore complex. Mol Cell Biol 16(5):2025-36 {{SGDpaper|S000046344}} PMID 8628268</ref><ref name='S000060228'>Kerscher O, et al. (2001) Novel role for a Saccharomyces cerevisiae nucleoporin, Nup170p, in chromosome segregation. Genetics 157(4):1543-53 {{SGDpaper|S000060228}} PMID 11290711</ref><ref name='S000130203'>Makio T, et al. (2009) The nucleoporins Nup170p and Nup157p are essential for nuclear pore complex assembly. J Cell Biol 185(3):459-73 {{SGDpaper|S000130203}} PMID 19414608</ref><ref name='S000146077'>Meinema AC, et al. (2011) Long unfolded linkers facilitate membrane protein import through the nuclear pore complex. Science 333(6038):90-3 {{SGDpaper|S000146077}} PMID 21659568</ref><ref name='S000056415'>Rout MP, et al. (2000) The yeast nuclear pore complex: composition, architecture, and transport mechanism. J Cell Biol 148(4):635-51 {{SGDpaper|S000056415}} PMID 10684247</ref><ref name='S000045804'>Shulga N, et al. (2000) Yeast nucleoporins involved in passive nuclear envelope permeability. J Cell Biol 149(5):1027-38 |
| − | {{SGDpaper| | + | {{SGDpaper|S000045804}} PMID 10831607</ref> |
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Latest revision as of 14:05, 11 June 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YBL079W |
| Gene name | NUP170 |
| Aliases | NLE3 |
| Feature type | ORF, Verified |
| Coordinates | Chr II:75259..79767 |
| Primary SGDID | S000000175 |
Description of YBL079W: Subunit of the inner ring of the nuclear pore complex (NPC); contributes to NPC assembly and nucleocytoplasmic transport; has similarity to Nup157p; both Nup170p and NUP157p are similar to human Nup155p[1][2][3][4][5][6][7][8][9]
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Contents
Community Commentary
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Alleles, Strains, and Phenotypes
Complete Deletion
Phenotype(s): Loss of function (Null)
Null mutants display defects in chromosome transmission fidelity and kinetochore integrity [5] [10]
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References
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- ↑ Aitchison JD, et al. (1995) Two novel related yeast nucleoporins Nup170p and Nup157p: complementation with the vertebrate homologue Nup155p and functional interactions with the yeast nuclear pore-membrane protein Pom152p. J Cell Biol 131(5):1133-48 SGD PMID 8522578
- ↑ Fernandez-Martinez J and Rout MP (2009) Nuclear pore complex biogenesis. Curr Opin Cell Biol 21(4):603-12 SGD PMID 19524430
- ↑ Iouk T, et al. (2002) The yeast nuclear pore complex functionally interacts with components of the spindle assembly checkpoint. J Cell Biol 159(5):807-19 SGD PMID 12473689
- ↑ Kenna MA, et al. (1996) Yeast N1e3p/Nup170p is required for normal stoichiometry of FG nucleoporins within the nuclear pore complex. Mol Cell Biol 16(5):2025-36 SGD PMID 8628268
- ↑ 5.0 5.1 Kerscher O, et al. (2001) Novel role for a Saccharomyces cerevisiae nucleoporin, Nup170p, in chromosome segregation. Genetics 157(4):1543-53 SGD PMID 11290711
- ↑ Makio T, et al. (2009) The nucleoporins Nup170p and Nup157p are essential for nuclear pore complex assembly. J Cell Biol 185(3):459-73 SGD PMID 19414608
- ↑ Meinema AC, et al. (2011) Long unfolded linkers facilitate membrane protein import through the nuclear pore complex. Science 333(6038):90-3 SGD PMID 21659568
- ↑ Rout MP, et al. (2000) The yeast nuclear pore complex: composition, architecture, and transport mechanism. J Cell Biol 148(4):635-51 SGD PMID 10684247
- ↑ Shulga N, et al. (2000) Yeast nucleoporins involved in passive nuclear envelope permeability. J Cell Biol 149(5):1027-38 SGD PMID 10831607
- ↑ submitted by Munira Basrai on 2005-07-29
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