Difference between revisions of "YBL050W"

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'''Description of YBL050W:''' Peripheral membrane protein required for vesicular transport between ER and Golgi and for the 'priming' step in homotypic vacuole fusion, part of the cis-SNARE complex; has similarity to alpha-SNAP<ref name='S000059553'>Wickner W and Haas A (2000) Yeast homotypic vacuole fusion: a window on organelle trafficking mechanisms. Annu Rev Biochem 69:247-75
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'''Description of YBL050W:''' Peripheral membrane protein required for vesicular transport between ER and Golgi, the 'priming' step in homotypic vacuole fusion, and autophagy; stimulates the ATPase activity of Sec18p; has similarity to mammalian alpha-SNAP<ref name='S000043228'>Griff IC, et al. (1992) The yeast SEC17 gene product is functionally equivalent to mammalian alpha-SNAP protein. J Biol Chem 267(17):12106-15 {{SGDpaper|S000043228}} PMID 1601878</ref><ref name='S000066273'>Ishihara N, et al. (2001) Autophagosome requires specific early Sec proteins for its formation and NSF/SNARE for vacuolar fusion. Mol Biol Cell 12(11):3690-702 {{SGDpaper|S000066273}} PMID 11694599</ref><ref name='S000052079'>Mayer A, et al. (1996) Sec18p (NSF)-driven release of Sec17p (alpha-SNAP) can precede docking and fusion of yeast vacuoles. Cell 85(1):83-94 {{SGDpaper|S000052079}} PMID 8620540</ref><ref name='S000046862'>Sogaard M, et al. (1994) A rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles. Cell 78(6):937-48 {{SGDpaper|S000046862}} PMID 7923363</ref><ref name='S000041605'>Steel GJ, et al. (1999) Biochemical analysis of the Saccharomyces cerevisiae SEC18 gene product: implications for the molecular mechanism of membrane fusion. Biochemistry 38(24):7764-72
  {{SGDpaper|S000059553}} PMID 10966459</ref>
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  {{SGDpaper|S000041605}} PMID 10387016</ref>
 
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Revision as of 14:05, 12 May 2010

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Systematic name YBL050W
Gene name SEC17
Aliases RNS3
Feature type ORF, Verified
Coordinates Chr II:125128..126122
Primary SGDID S000000146


Description of YBL050W: Peripheral membrane protein required for vesicular transport between ER and Golgi, the 'priming' step in homotypic vacuole fusion, and autophagy; stimulates the ATPase activity of Sec18p; has similarity to mammalian alpha-SNAP[1][2][3][4][5]




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References

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  1. Griff IC, et al. (1992) The yeast SEC17 gene product is functionally equivalent to mammalian alpha-SNAP protein. J Biol Chem 267(17):12106-15 SGD PMID 1601878
  2. Ishihara N, et al. (2001) Autophagosome requires specific early Sec proteins for its formation and NSF/SNARE for vacuolar fusion. Mol Biol Cell 12(11):3690-702 SGD PMID 11694599
  3. Mayer A, et al. (1996) Sec18p (NSF)-driven release of Sec17p (alpha-SNAP) can precede docking and fusion of yeast vacuoles. Cell 85(1):83-94 SGD PMID 8620540
  4. Sogaard M, et al. (1994) A rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles. Cell 78(6):937-48 SGD PMID 7923363
  5. Steel GJ, et al. (1999) Biochemical analysis of the Saccharomyces cerevisiae SEC18 gene product: implications for the molecular mechanism of membrane fusion. Biochemistry 38(24):7764-72 SGD PMID 10387016

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