Difference between revisions of "YBL016W"

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{|{{Prettytable}} align = 'right' width = '200px'
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YBL016W YBL016W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000000112 YBL016W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''FUS3 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''FUS3 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr II:192454..193515
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|nowrap| Chr II:192451..193512
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000000112
 
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'''Description of {{PAGENAME}}:''' Mitogen-activated protein kinase involved in mating pheromone response; activated by phosphorylation by Ste7p; provides specificity during the mating vs. filamentous growth response by phosphorylating transcriptional and cytoplasmic targets<ref name='S000080086'>Bao MZ, et al. (2004) Pheromone-dependent destruction of the Tec1 transcription factor is required for MAP kinase signaling specificity in yeast. Cell 119(7):991-1000 {{SGDpaper|S000080086}} PMID 15620357</ref><ref name='S000072725'>Ptashne M and Gann A (2003) Signal transduction. Imposing specificity on kinases. Science 299(5609):1025-7 {{SGDpaper|S000072725}} PMID 12586931</ref><ref name='S000071496'>Breitkreutz A and Tyers M (2002) MAPK signaling specificity: it takes two to tango. Trends Cell Biol 12(6):254-7
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'''Description of YBL016W:''' Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its degradation<ref name='S000080086'>Bao MZ, et al. (2004) Pheromone-dependent destruction of the Tec1 transcription factor is required for MAP kinase signaling specificity in yeast. Cell 119(7):991-1000 {{SGDpaper|S000080086}} PMID 15620357</ref><ref name='S000071496'>Breitkreutz A and Tyers M (2002) MAPK signaling specificity: it takes two to tango. Trends Cell Biol 12(6):254-7 {{SGDpaper|S000071496}} PMID 12074884</ref><ref name='S000044318'>Elion EA, et al. (1993) FUS3 phosphorylates multiple components of the mating signal transduction cascade: evidence for STE12 and FAR1. Mol Biol Cell 4(5):495-510 {{SGDpaper|S000044318}} PMID 8334305</ref><ref name='S000054539'>Garrison TR, et al. (1999) Feedback phosphorylation of an RGS protein by MAP kinase in yeast. J Biol Chem 274(51):36387-91 {{SGDpaper|S000054539}} PMID 10593933</ref><ref name='S000077121'>Matheos D, et al. (2004) Pheromone-induced polarization is dependent on the Fus3p MAPK acting through the formin Bni1p. J Cell Biol 165(1):99-109 {{SGDpaper|S000077121}} PMID 15067022</ref><ref name='S000072725'>Ptashne M and Gann A (2003) Signal transduction. Imposing specificity on kinases. Science 299(5609):1025-7
  {{SGDpaper|S000071496}} PMID 12074884</ref>
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  {{SGDpaper|S000072725}} PMID 12586931</ref>
 
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J Biol Chem 278(5):3265-74</ref>
 
J Biol Chem 278(5):3265-74</ref>
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YBL016W
Gene name FUS3
Aliases DAC2
Feature type ORF, Verified
Coordinates Chr II:192451..193512
Primary SGDID S000000112


Description of YBL016W: Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its degradation[1][2][3][4][5][6]




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References

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  1. Bao MZ, et al. (2004) Pheromone-dependent destruction of the Tec1 transcription factor is required for MAP kinase signaling specificity in yeast. Cell 119(7):991-1000 SGD PMID 15620357
  2. Breitkreutz A and Tyers M (2002) MAPK signaling specificity: it takes two to tango. Trends Cell Biol 12(6):254-7 SGD PMID 12074884
  3. Elion EA, et al. (1993) FUS3 phosphorylates multiple components of the mating signal transduction cascade: evidence for STE12 and FAR1. Mol Biol Cell 4(5):495-510 SGD PMID 8334305
  4. Garrison TR, et al. (1999) Feedback phosphorylation of an RGS protein by MAP kinase in yeast. J Biol Chem 274(51):36387-91 SGD PMID 10593933
  5. Matheos D, et al. (2004) Pheromone-induced polarization is dependent on the Fus3p MAPK acting through the formin Bni1p. J Cell Biol 165(1):99-109 SGD PMID 15067022
  6. Ptashne M and Gann A (2003) Signal transduction. Imposing specificity on kinases. Science 299(5609):1025-7 SGD PMID 12586931

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