Difference between revisions of "YAL028W"

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'''Description of YAL028W:''' Tail-anchored endoplasmic reticulum membrane protein, interacts with homolog Frt1p but is not a substrate of calcineurin (unlike Frt1p), promotes growth in conditions of high Na+, alkaline pH, or cell wall stress; potential Cdc28p substrate<ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 {{SGDpaper|S000074306}} PMID 14574415</ref><ref name='S000075375'>Burri L and Lithgow T (2004) A complete set of SNAREs in yeast. Traffic 5(1):45-52 {{SGDpaper|S000075375}} PMID 14675424</ref><ref name='S000059083'>Heath VL, et al. (2004) Hph1p and Hph2p, novel components of calcineurin-mediated stress responses in Saccharomyces cerevisiae. Eukaryot Cell 3(3):695-704
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'''Description of YAL028W:''' Tail-anchored endoplasmic reticulum membrane protein, interacts with homolog Frt1p but is not a substrate of calcineurin (unlike Frt1p), promotes growth in conditions of high Na+, alkaline pH, or cell wall stress; potential Cdc28p substrate<ref name='S000059083'>Heath VL, et al. (2004) Hph1p and Hph2p, novel components of calcineurin-mediated stress responses in Saccharomyces cerevisiae. Eukaryot Cell 3(3):695-704 {{SGDpaper|S000059083}} PMID 15189990</ref><ref name='S000075375'>Burri L and Lithgow T (2004) A complete set of SNAREs in yeast. Traffic 5(1):45-52 {{SGDpaper|S000075375}} PMID 14675424</ref><ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64
  {{SGDpaper|S000059083}} PMID 15189990</ref>
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  {{SGDpaper|S000074306}} PMID 14574415</ref>
 
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Revision as of 14:05, 16 January 2009

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Systematic name YAL028W
Gene name FRT2
Aliases HPH2
Feature type ORF, Verified
Coordinates Chr I:92901..94487
Primary SGDID S000000026


Description of YAL028W: Tail-anchored endoplasmic reticulum membrane protein, interacts with homolog Frt1p but is not a substrate of calcineurin (unlike Frt1p), promotes growth in conditions of high Na+, alkaline pH, or cell wall stress; potential Cdc28p substrate[1][2][3]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [3] [4]





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References

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  1. Heath VL, et al. (2004) Hph1p and Hph2p, novel components of calcineurin-mediated stress responses in Saccharomyces cerevisiae. Eukaryot Cell 3(3):695-704 SGD PMID 15189990
  2. Burri L and Lithgow T (2004) A complete set of SNAREs in yeast. Traffic 5(1):45-52 SGD PMID 14675424
  3. 3.0 3.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415 Cite error: Invalid <ref> tag; name "S000074306" defined multiple times with different content
  4. submitted by Jeff Ubersax on 2004-01-21

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