Difference between revisions of "RDN5-1"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=RDN5-1 RDN5-1]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006479 RDN5-1]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RDN5-1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RDN5-1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XII:459677..459797
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|nowrap| Chr XII:459676..459796
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000006479
 
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'''Description of {{PAGENAME}}:''' 5S ribosomal RNA, component of the large (60S) ribosomal subunit; localized to the nucleolus via interaction with Rpl5p; may play a role in maintenance of translational frame; transcription is mediated by PolIII and activated by TFIIIA<ref name='S000075498'>Michael WM and Dreyfuss G (1996) Distinct domains in ribosomal protein L5 mediate 5 S rRNA binding and nucleolar localization. J Biol Chem 271(19):11571-4 {{SGDpaper|S000075498}} PMID 8626719</ref><ref name='S000045219'>Camier S, et al. (1995) The only essential function of TFIIIA in yeast is the transcription of 5S rRNA genes. Proc Natl Acad Sci U S A 92(20):9338-42 {{SGDpaper|S000045219}} PMID 7568129</ref><ref name='S000044861'>Dinman JD and Wickner RB (1995) 5 S rRNA is involved in fidelity of translational reading frame. Genetics 141(1):95-105
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'''Description of RDN5-1:''' 5S ribosomal RNA (5S rRNA); only complete sequence of 6 repeated RDN5 alleles; able to support viability when provided as sole form of 5S rRNA; component of the large (60S) ribosomal subunit; localized to the nucleolus via interaction with Rpl5p; may play a role in translational frame fidelity; transcription is mediated by PolIII and activated by TFIIIA and TFIIIE<ref name='S000045219'>Camier S, et al. (1995) The only essential function of TFIIIA in yeast is the transcription of 5S rRNA genes. Proc Natl Acad Sci U S A 92(20):9338-42 {{SGDpaper|S000045219}} PMID 7568129</ref><ref name='S000128766'>Dieci G, et al. (2009) Positive modulation of RNA polymerase III transcription by ribosomal proteins. Biochem Biophys Res Commun 379(2):489-93 {{SGDpaper|S000128766}} PMID 19116144</ref><ref name='S000044861'>Dinman JD and Wickner RB (1995) 5 S rRNA is involved in fidelity of translational reading frame. Genetics 141(1):95-105 {{SGDpaper|S000044861}} PMID 8536994</ref><ref name='S000086205'>Kiparisov S, et al. (2005) Structural and functional analysis of 5S rRNA in Saccharomyces cerevisiae. Mol Genet Genomics 274(3):235-47 {{SGDpaper|S000086205}} PMID 16047201</ref><ref name='S000075498'>Michael WM and Dreyfuss G (1996) Distinct domains in ribosomal protein L5 mediate 5 S rRNA binding and nucleolar localization. J Biol Chem 271(19):11571-4
  {{SGDpaper|S000044861}} PMID 8536994</ref>
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  {{SGDpaper|S000075498}} PMID 8626719</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name RDN5-1
Gene name RDN5-1
Aliases RDN5
Feature type rRNA
Coordinates Chr XII:459676..459796
Primary SGDID S000006479


Description of RDN5-1: 5S ribosomal RNA (5S rRNA); only complete sequence of 6 repeated RDN5 alleles; able to support viability when provided as sole form of 5S rRNA; component of the large (60S) ribosomal subunit; localized to the nucleolus via interaction with Rpl5p; may play a role in translational frame fidelity; transcription is mediated by PolIII and activated by TFIIIA and TFIIIE[1][2][3][4][5]




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Community Commentary

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References

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  1. Camier S, et al. (1995) The only essential function of TFIIIA in yeast is the transcription of 5S rRNA genes. Proc Natl Acad Sci U S A 92(20):9338-42 SGD PMID 7568129
  2. Dieci G, et al. (2009) Positive modulation of RNA polymerase III transcription by ribosomal proteins. Biochem Biophys Res Commun 379(2):489-93 SGD PMID 19116144
  3. Dinman JD and Wickner RB (1995) 5 S rRNA is involved in fidelity of translational reading frame. Genetics 141(1):95-105 SGD PMID 8536994
  4. Kiparisov S, et al. (2005) Structural and functional analysis of 5S rRNA in Saccharomyces cerevisiae. Mol Genet Genomics 274(3):235-47 SGD PMID 16047201
  5. Michael WM and Dreyfuss G (1996) Distinct domains in ribosomal protein L5 mediate 5 S rRNA binding and nucleolar localization. J Biol Chem 271(19):11571-4 SGD PMID 8626719

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