YDR069C
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| Systematic name | YDR069C |
| Gene name | DOA4 |
| Aliases | DOS1, MUT4, NPI2, SSV7, UBP4 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:587719..584939 |
| Primary SGDID | S000002476 |
Description of YDR069C: Ubiquitin isopeptidase, required for recycling ubiquitin from proteasome-bound ubiquitinated intermediates, acts at the late endosome/prevacuolar compartment to recover ubiquitin from ubiquitinated membrane proteins en route to the vacuole[1][2][3]
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References
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- ↑ Amerik AY, et al. (2000) The Doa4 deubiquitinating enzyme is functionally linked to the vacuolar protein-sorting and endocytic pathways. Mol Biol Cell 11(10):3365-80 SGD PMID 11029042
- ↑ Singer JD, et al. (1996) Coordinating DNA replication to produce one copy of the genome requires genes that act in ubiquitin metabolism. Mol Cell Biol 16(4):1356-66 SGD PMID 8657109
- ↑ Swaminathan S, et al. (1999) The Doa4 deubiquitinating enzyme is required for ubiquitin homeostasis in yeast. Mol Biol Cell 10(8):2583-94 SGD PMID 10436014
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