YOR171C
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| Systematic name | YOR171C | |
| Gene name | LCB4 | |
| Aliases | ||
| Feature type | ORF, Verified | |
| Coordinates | Chr XV:653885..652011 | |
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Description of YOR171C: Sphingoid long-chain base kinase, responsible for synthesis of long-chain base phosphates, which function as signaling molecules, regulates synthesis of ceramide from exogenous long-chain bases, localizes to the Golgi and late endosomes[1][2][3][4]
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References
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- ↑ Martens JA, et al. (2004) Intergenic transcription is required to repress the Saccharomyces cerevisiae SER3 gene. Nature 429(6991):571-4 SGD PMID 15175754
- ↑ Funato K, et al. (2003) Lcb4p is a key regulator of ceramide synthesis from exogenous long chain sphingoid base in Saccharomyces cerevisiae. J Biol Chem 278(9):7325-34 SGD PMID 12493772
- ↑ Hait NC, et al. (2002) Lcb4p sphingoid base kinase localizes to the Golgi and late endosomes. FEBS Lett 532(1-2):97-102 SGD PMID 12459470
- ↑ Nagiec MM, et al. (1998) The LCB4 (YOR171c) and LCB5 (YLR260w) genes of Saccharomyces encode sphingoid long chain base kinases. J Biol Chem 273(31):19437-42 SGD PMID 9677363
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