YOR171C

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Systematic name YOR171C
Gene name LCB4
Aliases
Feature type ORF, Verified
Coordinates Chr XV:653884..652010
Primary SGDID S000005697


Description of YOR171C: Sphingoid long-chain base kinase, responsible for synthesis of long-chain base phosphates, which function as signaling molecules, regulates synthesis of ceramide from exogenous long-chain bases, localizes to the Golgi and late endosomes[1][2][3][4]




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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically lower expression in carbon limited chemostat cultures versus carbon excess. [5] [6]





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References

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  1. Funato K, et al. (2003) Lcb4p is a key regulator of ceramide synthesis from exogenous long chain sphingoid base in Saccharomyces cerevisiae. J Biol Chem 278(9):7325-34 SGD PMID 12493772
  2. Hait NC, et al. (2002) Lcb4p sphingoid base kinase localizes to the Golgi and late endosomes. FEBS Lett 532(1-2):97-102 SGD PMID 12459470
  3. Martens JA, et al. (2004) Intergenic transcription is required to repress the Saccharomyces cerevisiae SER3 gene. Nature 429(6991):571-4 SGD PMID 15175754
  4. Nagiec MM, et al. (1998) The LCB4 (YOR171c) and LCB5 (YLR260w) genes of Saccharomyces encode sphingoid long chain base kinases. J Biol Chem 273(31):19437-42 SGD PMID 9677363
  5. Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  6. submitted by Viktor Boer on 2003-07-25

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