YKL139W

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Systematic name YKL139W
Gene name CTK1
Aliases
Feature type ORF, Verified
Coordinates Chr XI:182963..184549
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Description of YKL139W: Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I), which phosphorylates the C-terminal repeated domain of the RNA polymerase II large subunit (Rpo21p) to affect both transcription and pre-mRNA 3' end processing[1][2]



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References

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  1. Skaar DA and Greenleaf AL (2002) The RNA polymerase II CTD kinase CTDK-I affects pre-mRNA 3' cleavage/polyadenylation through the processing component Pti1p. Mol Cell 10(6):1429-39 SGD PMID 12504017
  2. Lee JM and Greenleaf AL (1991) CTD kinase large subunit is encoded by CTK1, a gene required for normal growth of Saccharomyces cerevisiae. Gene Expr 1(2):149-67 SGD PMID 1820212

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