YKL089W

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Systematic name YKL089W
Gene name MIF2
Aliases
Feature type ORF, Verified
Coordinates Chr XI:273038..274687
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Description of YKL089W: Kinetochore protein with homology to human CENP-C, required for structural integrity of the spindle during anaphase spindle elongation, interacts with histones H2A, H2B, and H4, phosphorylated by Ipl1p[1][2][3]



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References

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  1. Westermann S, et al. (2003) Architecture of the budding yeast kinetochore reveals a conserved molecular core. J Cell Biol 163(2):215-22 SGD PMID 14581449
  2. Meluh PB and Koshland D (1995) Evidence that the MIF2 gene of Saccharomyces cerevisiae encodes a centromere protein with homology to the mammalian centromere protein CENP-C. Mol Biol Cell 6(7):793-807 SGD PMID 7579695
  3. Brown MT, et al. (1993) MIF2 is required for mitotic spindle integrity during anaphase spindle elongation in Saccharomyces cerevisiae. J Cell Biol 123(2):387-403 SGD PMID 8408221

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