YGR140W

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Systematic name YGR140W
Gene name CBF2
Aliases CBF3A, CEP2, CSL5, CTF14, NDC10
Feature type ORF, Verified
Coordinates Chr VII:767434..770304
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Description of YGR140W: Essential kinetochore protein, component of the CBF3 multisubunit complex that binds to the CDEIII region of the centromere; Cbf2p also binds to the CDEII region possibly forming a different multimeric complex, ubiquitinated in vivo[1][2][3]



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References

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  1. Espelin CW, et al. (2003) Binding of the essential Saccharomyces cerevisiae kinetochore protein Ndc10p to CDEII. Mol Biol Cell 14(11):4557-68 SGD PMID 13679521
  2. Yoon HJ and Carbon J (1995) Genetic and biochemical interactions between an essential kinetochore protein, Cbf2p/Ndc10p, and the CDC34 ubiquitin-conjugating enzyme. Mol Cell Biol 15(9):4835-42 SGD PMID 7651401
  3. Lechner J and Carbon J (1991) A 240 kd multisubunit protein complex, CBF3, is a major component of the budding yeast centromere. Cell 64(4):717-25 SGD PMID 1997204

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