YAL024C
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| Systematic name | YAL024C |
| Gene name | LTE1 |
| Aliases | MSI2 |
| Feature type | ORF, Verified |
| Coordinates | Chr I:105873..101566 |
| Primary SGDID | S000000022 |
Description of YAL024C: Putative GDP/GTP exchange factor required for mitotic exit at low temperatures; acts as a guanine nucleotide exchange factor (GEF) for Tem1p, which is a key regulator of mitotic exit; physically associates with Ras2p-GTP[1]
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [2] [3]
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References
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- ↑ Shirayama M, et al. (1994) Isolation of a CDC25 family gene, MSI2/LTE1, as a multicopy suppressor of ira1. Yeast 10(4):451-61 SGD PMID 7941731
- ↑ Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ submitted by Jeff Ubersax on 2004-01-21
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