YHR086W

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Systematic name YHR086W
Gene name NAM8
Aliases MRE2, MUD15
Feature type ORF, Verified
Coordinates Chr VIII:278155..279726


Description of YHR086W: RNA binding protein, component of the U1 snRNP protein; mutants are defective in meiotic recombination and in formation of viable spores, involved in the formation of DSBs through meiosis-specific splicing of MER2 pre-mRNA[1][2][3]




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References

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  1. Ogawa H, et al. (1995) Functions of the yeast meiotic recombination genes, MRE11 and MRE2. Adv Biophys 31():67-76 SGD PMID 7625279
  2. Puig O, et al. (1999) Interaction of the U1 snRNP with nonconserved intronic sequences affects 5' splice site selection. Genes Dev 13(5):569-80 SGD PMID 10072385
  3. Nakagawa T and Ogawa H (1997) Involvement of the MRE2 gene of yeast in formation of meiosis-specific double-strand breaks and crossover recombination through RNA splicing. Genes Cells 2(1):65-79 SGD PMID 9112441

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