YDL074C

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Systematic name YDL074C
Gene name BRE1
Aliases
Feature type ORF, Verified
Coordinates Chr IV:326149..324047
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Description of YDL074C: E3 ubiquitin ligase for Rad6p, required for the ubiquitination of histone H2B, recruitment of Rad6p to promoter chromatin and subsequent methylation of histone H3 (on L4 and L79), contains RING finger domain[1]



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References

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  1. ↑ Wood A, et al. (2003) Bre1, an E3 ubiquitin ligase required for recruitment and substrate selection of Rad6 at a promoter. Mol Cell 11(1):267-74 SGD PMID 12535539

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