YBL052C
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| Systematic name | YBL052C | |
| Gene name | SAS3 | |
| Aliases | ||
| Feature type | ORF, Verified | |
| Coordinates | Chr II:121877..119382 | |
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Description of YBL052C: Histone acetyltransferase catalytic subunit of NuA3 complex that acetylates histone H3, involved in transcriptional silencing; homolog of the mammalian MOZ proto-oncogene; sas3 gcn5 double mutation confers lethality[1][2][3]
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References
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- Jump up ↑ Howe L, et al. (2001) Histone H3 specific acetyltransferases are essential for cell cycle progression. Genes Dev 15(23):3144-54 SGD PMID 11731478
- Jump up ↑ John S, et al. (2000) The something about silencing protein, Sas3, is the catalytic subunit of NuA3, a yTAF(II)30-containing HAT complex that interacts with the Spt16 subunit of the yeast CP (Cdc68/Pob3)-FACT complex. Genes Dev 14(10):1196-208 SGD PMID 10817755
- Jump up ↑ Reifsnyder C, et al. (1996) Yeast SAS silencing genes and human genes associated with AML and HIV-1 Tat interactions are homologous with acetyltransferases. Nat Genet 14(1):42-9 SGD PMID 8782818
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