YGR112W

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Systematic name YGR112W
Gene name SHY1
Aliases
Feature type ORF, Verified
Coordinates Chr VII:717362..718531


Description of YGR112W: Mitochondrial inner membrane protein required for normal respiration, possible chaperone involved in assembly of cytochrome c oxidase; similar to SURF1 from mammals, chickens, and D. melanogaster[1][2]




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References

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  1. Barrientos A, et al. (2002) Shy1p is necessary for full expression of mitochondrial COX1 in the yeast model of Leigh's syndrome. EMBO J 21(1-2):43-52 SGD PMID 11782424
  2. Mashkevich G, et al. (1997) SHY1, the yeast homolog of the mammalian SURF-1 gene, encodes a mitochondrial protein required for respiration. J Biol Chem 272(22):14356-64 SGD PMID 9162072

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