YBL106C

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Systematic name YBL106C
Gene name SRO77
Aliases SNI2, SOP2
Feature type ORF, Verified
Coordinates Chr II:13879..10847


Description of YBL106C: Protein with roles in exocytosis and cation homeostasis; functions in docking and fusion of post-Golgi vesicles with plasma membrane; homolog of Sro7p and Drosophila lethal giant larvae tumor suppressor; interacts with SNARE protein Sec9p[1][2][3]




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References

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  1. Wadskog I, et al. (2004) Yeast lacking the SRO7/SOP1-encoded tumor suppressor homologue show increased susceptibility to apoptosis-like cell death on exposure to NaCl stress. Mol Biol Cell 15(3):1436-44 SGD PMID 14718573
  2. Larsson K, et al. (1998) The Saccharomyces cerevisiae SOP1 and SOP2 genes, which act in cation homeostasis, can be functionally substituted by the Drosophila lethal(2)giant larvae tumor suppressor gene. J Biol Chem 273(50):33610-8 SGD PMID 9837945
  3. Lehman K, et al. (1999) Yeast homologues of tomosyn and lethal giant larvae function in exocytosis and are associated with the plasma membrane SNARE, Sec9. J Cell Biol 146(1):125-40 SGD PMID 10402465

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