YBL106C

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Systematic name YBL106C
Gene name SRO77
Aliases SNI2, SOP2
Feature type ORF, Verified
Coordinates Chr II:13879..10847
Primary SGDID S000000202


Description of YBL106C: Protein with roles in exocytosis and cation homeostasis; functions in docking and fusion of post-Golgi vesicles with plasma membrane; homolog of Sro7p and Drosophila lethal giant larvae tumor suppressor; interacts with SNARE protein Sec9p[1][2][3]




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References

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  1. Larsson K, et al. (1998) The Saccharomyces cerevisiae SOP1 and SOP2 genes, which act in cation homeostasis, can be functionally substituted by the Drosophila lethal(2)giant larvae tumor suppressor gene. J Biol Chem 273(50):33610-8 SGD PMID 9837945
  2. Lehman K, et al. (1999) Yeast homologues of tomosyn and lethal giant larvae function in exocytosis and are associated with the plasma membrane SNARE, Sec9. J Cell Biol 146(1):125-40 SGD PMID 10402465
  3. Wadskog I, et al. (2004) Yeast lacking the SRO7/SOP1-encoded tumor suppressor homologue show increased susceptibility to apoptosis-like cell death on exposure to NaCl stress. Mol Biol Cell 15(3):1436-44 SGD PMID 14718573

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