YLR193C
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| Systematic name | YLR193C |
| Gene name | UPS1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:540538..540011 |
| Primary SGDID | S000004183 |
Description of YLR193C: Mitochondrial intermembrane space protein that regulates mitochondrial cardiolipin levels, null has defects in Mgm1p processing, integrity of mitochondrial inner membrane complexes, and mitochondrial morphology; ortholog of human PRELI[1][2][3][4]
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References
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- ↑ Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
- ↑ Osman C, et al. (2009) The genetic interactome of prohibitins: coordinated control of cardiolipin and phosphatidylethanolamine by conserved regulators in mitochondria. J Cell Biol 184(4):583-96 SGD PMID 19221197
- ↑ Sesaki H, et al. (2006) Ups1p, a conserved intermembrane space protein, regulates mitochondrial shape and alternative topogenesis of Mgm1p. J Cell Biol 173(5):651-8 SGD PMID 16754953
- ↑ Tamura Y, et al. (2009) Ups1p and Ups2p antagonistically regulate cardiolipin metabolism in mitochondria. J Cell Biol 185(6):1029-45 SGD PMID 19506038
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