YJR047C
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| Systematic name | YJR047C |
| Gene name | ANB1 |
| Aliases | HYP1, TIF51B, eIF-5A |
| Feature type | ORF, Verified |
| Coordinates | Chr X:525373..524900 |
| Primary SGDID | S000003808 |
Description of YJR047C: Translation elongation factor eIF-5A, previously thought to function in translation initiation; similar to and functionally redundant with Hyp2p; undergoes an essential hypusination modification; expressed under anaerobic conditions[1][2][3][4]
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References
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- ↑ Kang HA, et al. (1993) Translation initiation factor eIF-5A, the hypusine-containing protein, is phosphorylated on serine in Saccharomyces cerevisiae. J Biol Chem 268(20):14750-6 SGD PMID 8325852
- ↑ Saini P, et al. (2009) Hypusine-containing protein eIF5A promotes translation elongation. Nature 459(7243):118-21 SGD PMID 19424157
- ↑ Schnier J, et al. (1991) Translation initiation factor 5A and its hypusine modification are essential for cell viability in the yeast Saccharomyces cerevisiae. Mol Cell Biol 11(6):3105-14 SGD PMID 1903841
- ↑ Schwelberger HG, et al. (1993) Translation initiation factor eIF-5A expressed from either of two yeast genes or from human cDNA. Functional identity under aerobic and anaerobic conditions. J Biol Chem 268(19):14018-25 SGD PMID 8314769
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