YIL083C
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Systematic name | YIL083C |
Gene name | CAB2 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr IX:204650..203553 |
Primary SGDID | S000001345 |
Description of YIL083C: Probable phosphopantothenoylcysteine synthetase (PPCS), which catalyzes the second step of coenzyme A biosynthesis from pantothenate; null mutant lethality is complemented by E. coli coaBC (encoding a bifunctional enzyme with PPCS activity)[1][2][3]
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References
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- ↑ Daugherty M, et al. (2002) Complete reconstitution of the human coenzyme A biosynthetic pathway via comparative genomics. J Biol Chem 277(24):21431-9 SGD PMID 11923312
- ↑ Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 SGD PMID 12140549
- ↑ Olzhausen J, et al. (2009) Genetic analysis of coenzyme A biosynthesis in the yeast Saccharomyces cerevisiae: identification of a conditional mutation in the pantothenate kinase gene CAB1. Curr Genet 55(2):163-73 SGD PMID 19266201
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