YIL083C

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Systematic name YIL083C
Gene name CAB2
Aliases
Feature type ORF, Verified
Coordinates Chr IX:204653..203556
Primary SGDID S000001345


Description of YIL083C: Probable phosphopantothenoylcysteine synthetase (PPCS), which catalyzes the second step of coenzyme A biosynthesis from pantothenate; null mutant lethality is complemented by E. coli coaBC (encoding a bifunctional enzyme with PPCS activity)[1][2][3]




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References

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  1. Daugherty M, et al. (2002) Complete reconstitution of the human coenzyme A biosynthetic pathway via comparative genomics. J Biol Chem 277(24):21431-9 SGD PMID 11923312
  2. Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 SGD PMID 12140549
  3. Olzhausen J, et al. (2009) Genetic analysis of coenzyme A biosynthesis in the yeast Saccharomyces cerevisiae: identification of a conditional mutation in the pantothenate kinase gene CAB1. Curr Genet 55(2):163-73 SGD PMID 19266201

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