YBL079W
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| Systematic name | YBL079W |
| Gene name | NUP170 |
| Aliases | NLE3 |
| Feature type | ORF, Verified |
| Coordinates | Chr II:75256..79764 |
| Primary SGDID | S000000175 |
Description of YBL079W: Subunit of the nuclear pore complex (NPC), required for NPC localization of specific nucleoporins; involved in nuclear envelope permeability and chromosome segregation; has similar to Nup157p; essential role, with Nup157p, in NPC assembly[1][2][3][4][5][6]
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Contents
Community Commentary
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Alleles, Strains, and Phenotypes
Complete Deletion
Phenotype(s): Loss of function (Null)
Null mutants display defects in chromosome transmission fidelity and kinetochore integrity [5] [7]
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References
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- ↑ Shulga N, et al. (2000) Yeast nucleoporins involved in passive nuclear envelope permeability. J Cell Biol 149(5):1027-38 SGD PMID 10831607
- ↑ Kenna MA, et al. (1996) Yeast N1e3p/Nup170p is required for normal stoichiometry of FG nucleoporins within the nuclear pore complex. Mol Cell Biol 16(5):2025-36 SGD PMID 8628268
- ↑ Rout MP, et al. (2000) The yeast nuclear pore complex: composition, architecture, and transport mechanism. J Cell Biol 148(4):635-51 SGD PMID 10684247
- ↑ Aitchison JD, et al. (1995) Two novel related yeast nucleoporins Nup170p and Nup157p: complementation with the vertebrate homologue Nup155p and functional interactions with the yeast nuclear pore-membrane protein Pom152p. J Cell Biol 131(5):1133-48 SGD PMID 8522578
- ↑ 5.0 5.1 Kerscher O, et al. (2001) Novel role for a Saccharomyces cerevisiae nucleoporin, Nup170p, in chromosome segregation. Genetics 157(4):1543-53 SGD PMID 11290711
- ↑ Makio T, et al. (2009) The nucleoporins Nup170p and Nup157p are essential for nuclear pore complex assembly. J Cell Biol 185(3):459-73 SGD PMID 19414608
- ↑ submitted by Munira Basrai on 2005-07-29
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