YLR396C
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Systematic name | YLR396C |
Gene name | VPS33 |
Aliases | CLS14, MET27, PEP14, SLP1, VAM5, VPL25, VPT33 |
Feature type | ORF, Verified |
Coordinates | Chr XII:912310..910235 |
Primary SGDID | S000004388 |
Description of YLR396C: ATP-binding protein that is a subunit of the HOPS complex and the CORVET tethering complex; essential for membrane docking and fusion at both the Golgi-to-endosome and endosome-to-vacuole stages of protein transport[1][2][3][4]
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References
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- ↑ Seals DF, et al. (2000) A Ypt/Rab effector complex containing the Sec1 homolog Vps33p is required for homotypic vacuole fusion. Proc Natl Acad Sci U S A 97(17):9402-7 SGD PMID 10944212
- ↑ Gerhardt B, et al. (1998) The vesicle transport protein Vps33p is an ATP-binding protein that localizes to the cytosol in an energy-dependent manner. J Biol Chem 273(25):15818-29 SGD PMID 9624182
- ↑ Peterson MR and Emr SD (2001) The class C Vps complex functions at multiple stages of the vacuolar transport pathway. Traffic 2(7):476-86 SGD PMID 11422941
- ↑ Peplowska K, et al. (2007) The CORVET Tethering Complex Interacts with the Yeast Rab5 Homolog Vps21 and Is Involved in Endo-Lysosomal Biogenesis. Dev Cell 12(5):739-50 SGD PMID 17488625
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