YJR050W
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| Systematic name | YJR050W |
| Gene name | ISY1 |
| Aliases | NTC30, UTR3 |
| Feature type | ORF, Verified |
| Coordinates | Chr X:528689..529396 |
| Primary SGDID | S000003811 |
Description of YJR050W: Component of the spliceosome complex involved in pre-mRNA splicing, auxiliary splicing factor that may modulate Syf1p activity and help optimize splicing; isy1 syf2 double mutation activates the spindle checkpoint, causing cell cycle arrest[1][2][3]
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References
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- ↑ Chen CH, et al. (2001) Identification and characterization of two novel components of the Prp19p-associated complex, Ntc30p and Ntc20p. J Biol Chem 276(1):488-94 SGD PMID 11018040
- ↑ Chen CH, et al. (2002) Functional and physical interactions between components of the Prp19p-associated complex. Nucleic Acids Res 30(4):1029-37 SGD PMID 11842115
- ↑ Dahan O and Kupiec M (2002) Mutations in genes of Saccharomyces cerevisiae encoding pre-mRNA splicing factors cause cell cycle arrest through activation of the spindle checkpoint. Nucleic Acids Res 30(20):4361-70 SGD PMID 12384582
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