YEL019C
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| Systematic name | YEL019C |
| Gene name | MMS21 |
| Aliases | NSE2, PSO10 |
| Feature type | ORF, Verified |
| Coordinates | Chr V:121301..120498 |
| Primary SGDID | S000000745 |
Description of YEL019C: SUMO ligase involved in chromosomal organization and DNA repair; essential subunit of the Mms21-Smc5-Smc6 complex; mutants are sensitive to methyl methanesulfonate and show increased spontaneous mutation and mitotic recombination[1][2][3]
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References
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- ↑ Prakash S and Prakash L (1977) Increased spontaneous mitotic segregation in MMS-sensitive mutants of Saccharomyces cerevisiae. Genetics 87(2):229-36 SGD PMID 200524
- ↑ Montelone BA and Koelliker KJ (1995) Interactions among mutations affecting spontaneous mutation, mitotic recombination, and DNA repair in yeast. Curr Genet 27(2):102-9 SGD PMID 7788712
- ↑ Zhao X and Blobel G (2005) A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization. Proc Natl Acad Sci U S A 102(13):4777-82 SGD PMID 15738391
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