YCL017C
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| Systematic name | YCL017C |
| Gene name | NFS1 |
| Aliases | SPL1 |
| Feature type | ORF, Verified |
| Coordinates | Chr III:94270..92777 |
| Primary SGDID | S000000522 |
Description of YCL017C: Cysteine desulfurase involved in iron-sulfur cluster (Fe/S) biogenesis; required for the post-transcriptional thio-modification of mitochondrial and cytoplasmic tRNAs; essential protein located predominantly in mitochondria[1][2][3]
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References
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- ↑ Kispal G, et al. (1999) The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe/S proteins. EMBO J 18(14):3981-9 SGD PMID 10406803
- ↑ Nakai Y, et al. (2004) Yeast Nfs1p is involved in thio-modification of both mitochondrial and cytoplasmic tRNAs. J Biol Chem 279(13):12363-8 SGD PMID 14722066
- ↑ Muhlenhoff U, et al. (2004) Functional characterization of the eukaryotic cysteine desulfurase Nfs1p from Saccharomyces cerevisiae. J Biol Chem 279(35):36906-15 SGD PMID 15220327
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