YIR011C
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| Systematic name | YIR011C |
| Gene name | STS1 |
| Aliases | DBF8, SSM5 |
| Feature type | ORF, Verified |
| Coordinates | Chr IX:378246..377287 |
| Primary SGDID | S000001450 |
Description of YIR011C: Protein required for localizing proteasomes to the nucleus; interacts with the karyopherin Srp1p; involved in ubiquitin-mediated protein degradation[1][2][3]
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References
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- ↑ Amrani N, et al. (1996) Mutations in STS1 suppress the defect in 3' mRNA processing caused by the rna15-2 mutation in Saccharomyces cerevisiae. Mol Gen Genet 252(5):552-62 SGD PMID 8914516
- ↑ Chen L, et al. (2011) Sts1 plays a key role in targeting proteasomes to the nucleus. J Biol Chem 286(4):3104-18 SGD PMID 21075847
- ↑ Tabb MM, et al. (2000) Evidence for separable functions of Srp1p, the yeast homolog of importin alpha (Karyopherin alpha): role for Srp1p and Sts1p in protein degradation. Mol Cell Biol 20(16):6062-73 SGD PMID 10913188
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