YIR011C

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Systematic name YIR011C
Gene name STS1
Aliases DBF8, SSM5
Feature type ORF, Verified
Coordinates Chr IX:378246..377287
Primary SGDID S000001450


Description of YIR011C: Protein required for localizing proteasomes to the nucleus; interacts with the karyopherin Srp1p; involved in ubiquitin-mediated protein degradation[1][2][3]




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References

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  1. Amrani N, et al. (1996) Mutations in STS1 suppress the defect in 3' mRNA processing caused by the rna15-2 mutation in Saccharomyces cerevisiae. Mol Gen Genet 252(5):552-62 SGD PMID 8914516
  2. Chen L, et al. (2011) Sts1 plays a key role in targeting proteasomes to the nucleus. J Biol Chem 286(4):3104-18 SGD PMID 21075847
  3. Tabb MM, et al. (2000) Evidence for separable functions of Srp1p, the yeast homolog of importin alpha (Karyopherin alpha): role for Srp1p and Sts1p in protein degradation. Mol Cell Biol 20(16):6062-73 SGD PMID 10913188

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