YGL095C
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| Systematic name | YGL095C |
| Gene name | VPS45 |
| Aliases | STT10, VPL28 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:330610..328877 |
| Primary SGDID | S000003063 |
Description of YGL095C: Protein of the Sec1p/Munc-18 family, essential for vacuolar protein sorting; required for the function of Pep12p and the early endosome/late Golgi SNARE Tlg2p; essential for fusion of Golgi-derived vesicles with the prevacuolar compartment[1][2][3]
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References
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- ↑ Piper RC, et al. (1994) Yeast Vps45p is a Sec1p-like protein required for the consumption of vacuole-targeted, post-Golgi transport vesicles. Eur J Cell Biol 65(2):305-18 SGD PMID 7720726
- ↑ Bryant NJ, et al. (1998) Traffic into the prevacuolar/endosomal compartment of Saccharomyces cerevisiae: a VPS45-dependent intracellular route and a VPS45-independent, endocytic route. Eur J Cell Biol 76(1):43-52 SGD PMID 9650782
- ↑ Bryant NJ and James DE (2001) Vps45p stabilizes the syntaxin homologue Tlg2p and positively regulates SNARE complex formation. EMBO J 20(13):3380-8 SGD PMID 11432826
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