YGL095C

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Systematic name YGL095C
Gene name VPS45
Aliases STT10, VPL28
Feature type ORF, Verified
Coordinates Chr VII:330607..328874
Primary SGDID S000003063


Description of YGL095C: Protein of the Sec1p/Munc-18 family, essential for vacuolar protein sorting; required for the function of Pep12p and the early endosome/late Golgi SNARE Tlg2p; essential for fusion of Golgi-derived vesicles with the prevacuolar compartment[1][2][3]




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References

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  1. Bryant NJ and James DE (2001) Vps45p stabilizes the syntaxin homologue Tlg2p and positively regulates SNARE complex formation. EMBO J 20(13):3380-8 SGD PMID 11432826
  2. Bryant NJ, et al. (1998) Traffic into the prevacuolar/endosomal compartment of Saccharomyces cerevisiae: a VPS45-dependent intracellular route and a VPS45-independent, endocytic route. Eur J Cell Biol 76(1):43-52 SGD PMID 9650782
  3. Piper RC, et al. (1994) Yeast Vps45p is a Sec1p-like protein required for the consumption of vacuole-targeted, post-Golgi transport vesicles. Eur J Cell Biol 65(2):305-18 SGD PMID 7720726

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