YBR156C

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Systematic name YBR156C
Gene name SLI15
Aliases
Feature type ORF, Verified
Coordinates Chr II:553194..551098
Primary SGDID S000000360


Description of YBR156C: Subunit of the Ipl1p-Sli15p-Bir1p complex that regulates kinetochore-microtubule attachments, activation of the spindle tension checkpoint, and mitotic spindle disassembly; regulates the activity and localization of the Ipl1p aurora kinase[1][2][3][4][5]




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References

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  1. D'Amours D and Amon A (2004) At the interface between signaling and executing anaphase--Cdc14 and the FEAR network. Genes Dev 18(21):2581-95 SGD PMID 15520278
  2. Buvelot S, et al. (2003) The budding yeast Ipl1/Aurora protein kinase regulates mitotic spindle disassembly. J Cell Biol 160(3):329-39 SGD PMID 12566427
  3. Tanaka TU, et al. (2002) Evidence that the Ipl1-Sli15 (Aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connections. Cell 108(3):317-29 SGD PMID 11853667
  4. Biggins S and Murray AW (2001) The budding yeast protein kinase Ipl1/Aurora allows the absence of tension to activate the spindle checkpoint. Genes Dev 15(23):3118-29 SGD PMID 11731476
  5. Kim JH, et al. (1999) Sli15 associates with the ipl1 protein kinase to promote proper chromosome segregation in Saccharomyces cerevisiae. J Cell Biol 145(7):1381-94 SGD PMID 10385519

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