YBR156C

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Systematic name YBR156C
Gene name SLI15
Aliases
Feature type ORF, Verified
Coordinates Chr II:553200..551104
Primary SGDID S000000360


Description of YBR156C: Subunit of the conserved chromosomal passenger complex (CPC; Ipl1p-Sli15p-Bir1p-Nbl1p), which regulates kinetochore-microtubule attachments, activation of the spindle tension checkpoint, and mitotic spindle disassembly[1][2][3][4][5][6]




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References

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  1. Biggins S and Murray AW (2001) The budding yeast protein kinase Ipl1/Aurora allows the absence of tension to activate the spindle checkpoint. Genes Dev 15(23):3118-29 SGD PMID 11731476
  2. Buvelot S, et al. (2003) The budding yeast Ipl1/Aurora protein kinase regulates mitotic spindle disassembly. J Cell Biol 160(3):329-39 SGD PMID 12566427
  3. D'Amours D and Amon A (2004) At the interface between signaling and executing anaphase--Cdc14 and the FEAR network. Genes Dev 18(21):2581-95 SGD PMID 15520278
  4. Kim JH, et al. (1999) Sli15 associates with the ipl1 protein kinase to promote proper chromosome segregation in Saccharomyces cerevisiae. J Cell Biol 145(7):1381-94 SGD PMID 10385519
  5. Nakajima Y, et al. (2009) Nbl1p: a Borealin/Dasra/CSC-1-like protein essential for Aurora/Ipl1 complex function and integrity in Saccharomyces cerevisiae. Mol Biol Cell 20(6):1772-84 SGD PMID 19158380
  6. Tanaka TU, et al. (2002) Evidence that the Ipl1-Sli15 (Aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connections. Cell 108(3):317-29 SGD PMID 11853667

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