YNL015W
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| Systematic name | YNL015W |
| Gene name | PBI2 |
| Aliases | I2B, IB2, LMA1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:605386..605613 |
| Primary SGDID | S000004960 |
Description of YNL015W: Cytosolic inhibitor of vacuolar proteinase B (PRB1), required for efficient vacuole inheritance; with thioredoxin forms protein complex LMA1, which assists in priming SNARE molecules and promotes vacuole fusion[1][2][3][4]
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References
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- ↑ Betz H (1975) Levels and turnover of the proteinase B inhibitors in yeast. Biochim Biophys Acta 404(1):142-51 SGD PMID 1100120
- ↑ Elazar Z, et al. (2003) Involvement of LMA1 and GATE-16 family members in intracellular membrane dynamics. Biochim Biophys Acta 1641(2-3):145-56 SGD PMID 12914955
- ↑ Slusarewicz P, et al. (1997) I2B is a small cytosolic protein that participates in vacuole fusion. Proc Natl Acad Sci U S A 94(11):5582-7 SGD PMID 9159115
- ↑ Xu Z, et al. (1997) A heterodimer of thioredoxin and I(B)2 cooperates with Sec18p (NSF) to promote yeast vacuole inheritance. J Cell Biol 136(2):299-306 SGD PMID 9015301
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