From SGD-Wiki
Jump to: navigation, search

Share your knowledge...Edit this entry! <protect>

Systematic name YNL015W
Gene name PBI2
Aliases I2B, IB2, LMA1
Feature type ORF, Verified
Coordinates Chr XIV:605384..605611
Primary SGDID S000004960

Description of YNL015W: Cytosolic inhibitor of vacuolar proteinase B (PRB1), required for efficient vacuole inheritance; with thioredoxin forms protein complex LMA1, which assists in priming SNARE molecules and promotes vacuole fusion[1][2][3][4]


Community Commentary

About Community Commentary. Please share your knowledge!



See Help:References on how to add references

  1. Betz H (1975) Levels and turnover of the proteinase B inhibitors in yeast. Biochim Biophys Acta 404(1):142-51 SGD PMID 1100120
  2. Elazar Z, et al. (2003) Involvement of LMA1 and GATE-16 family members in intracellular membrane dynamics. Biochim Biophys Acta 1641(2-3):145-56 SGD PMID 12914955
  3. Slusarewicz P, et al. (1997) I2B is a small cytosolic protein that participates in vacuole fusion. Proc Natl Acad Sci U S A 94(11):5582-7 SGD PMID 9159115
  4. Xu Z, et al. (1997) A heterodimer of thioredoxin and I(B)2 cooperates with Sec18p (NSF) to promote yeast vacuole inheritance. J Cell Biol 136(2):299-306 SGD PMID 9015301

See Help:Categories on how to add the wiki page for this gene to a Category </protect>