YGL004C

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Systematic name YGL004C
Gene name RPN14
Aliases
Feature type ORF, Verified
Coordinates Chr VII:491960..490707
Primary SGDID S000002972


Description of YGL004C: Proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasome regulatory particle (RP); null mutants accumulate ubiquitinated Gcn4p and display decreased 26S proteasome stability; interacts with Rpt5p[1][2][3][4][5][6]




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References

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  1. Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
  2. Samanta MP and Liang S (2003) Predicting protein functions from redundancies in large-scale protein interaction networks. Proc Natl Acad Sci U S A 100(22):12579-83 SGD PMID 14566057
  3. Seong KM, et al. (2007) Rpn13p and Rpn14p are involved in the recognition of ubiquitinated Gcn4p by the 26S proteasome. FEBS Lett 581(13):2567-73 SGD PMID 17499717
  4. Saeki Y, et al. (2009) Multiple Proteasome-Interacting Proteins Assist the Assembly of the Yeast 19S Regulatory Particle. Cell SGD PMID 19446323
  5. Funakoshi M, et al. (2009) Multiple Assembly Chaperones Govern Biogenesis of the Proteasome Regulatory Particle Base. Cell SGD PMID 19446322
  6. Roelofs J, et al. (2009) Chaperone-mediated pathway of proteasome regulatory particle assembly. Nature SGD PMID 19412159

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