YGL004C

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Systematic name YGL004C
Gene name RPN14
Aliases
Feature type ORF, Verified
Coordinates Chr VII:491956..490703
Primary SGDID S000002972


Description of YGL004C: Proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasome regulatory particle (RP); null mutants accumulate ubiquitinated Gcn4p and display decreased 26S proteasome stability; interacts with Rpt5p[1][2][3][4][5][6]




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References

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  1. Funakoshi M, et al. (2009) Multiple assembly chaperones govern biogenesis of the proteasome regulatory particle base. Cell 137(5):887-99 SGD PMID 19446322
  2. Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
  3. Roelofs J, et al. (2009) Chaperone-mediated pathway of proteasome regulatory particle assembly. Nature 459(7248):861-5 SGD PMID 19412159
  4. Saeki Y, et al. (2009) Multiple proteasome-interacting proteins assist the assembly of the yeast 19S regulatory particle. Cell 137(5):900-13 SGD PMID 19446323
  5. Samanta MP and Liang S (2003) Predicting protein functions from redundancies in large-scale protein interaction networks. Proc Natl Acad Sci U S A 100(22):12579-83 SGD PMID 14566057
  6. Seong KM, et al. (2007) Rpn13p and Rpn14p are involved in the recognition of ubiquitinated Gcn4p by the 26S proteasome. FEBS Lett 581(13):2567-73 SGD PMID 17499717

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