YKL139W
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| Systematic name | YKL139W |
| Gene name | CTK1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:182963..184549 |
| Primary SGDID | S000001622 |
Description of YKL139W: Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I), which phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3' end processing, and ribosomal protein Rps2p to increase translational fidelity[1][2][3]
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References
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- ↑ Lee JM and Greenleaf AL (1991) CTD kinase large subunit is encoded by CTK1, a gene required for normal growth of Saccharomyces cerevisiae. Gene Expr 1(2):149-67 SGD PMID 1820212
- ↑ Rother S and Strasser K (2007) The RNA polymerase II CTD kinase Ctk1 functions in translation elongation. Genes Dev 21(11):1409-21 SGD PMID 17545469
- ↑ Skaar DA and Greenleaf AL (2002) The RNA polymerase II CTD kinase CTDK-I affects pre-mRNA 3' cleavage/polyadenylation through the processing component Pti1p. Mol Cell 10(6):1429-39 SGD PMID 12504017
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