Difference between revisions of "YEL058W"
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| − | '''Description of YEL058W:''' Essential N-acetylglucosamine-phosphate mutase, a | + | '''Description of YEL058W:''' Essential N-acetylglucosamine-phosphate mutase; converts GlcNAc-6-P to GlcNAc-1-P, which is a precursor for the biosynthesis of chitin and for the formation of N-glycosylated mannoproteins and glycosylphosphatidylinositol anchors<ref name='S000054480'>Igual JC, et al. (1997) A genetic screen reveals a role for the late G1-specific transcription factor Swi4p in diverse cellular functions including cytokinesis. J Cell Sci 110 ( Pt 14):1647-54 {{SGDpaper|S000054480}} PMID 9247198</ref><ref name='S000047874'>Hofmann M, et al. (1994) Characterization of the essential yeast gene encoding N-acetylglucosamine-phosphate mutase. Eur J Biochem 221(2):741-7 {{SGDpaper|S000047874}} PMID 8174553</ref><ref name='S000039664'>Mio T, et al. (2000) Functional cloning and mutational analysis of the human cDNA for phosphoacetylglucosamine mutase: identification of the amino acid residues essential for the catalysis. Biochim Biophys Acta 1492(2-3):369-76 |
{{SGDpaper|S000039664}} PMID 11004509</ref> | {{SGDpaper|S000039664}} PMID 11004509</ref> | ||
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Revision as of 13:05, 11 October 2007
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| Systematic name | YEL058W |
| Gene name | PCM1 |
| Aliases | AGM1 |
| Feature type | ORF, Verified |
| Coordinates | Chr V:43252..44925 |
| Primary SGDID | S000000784 |
Description of YEL058W: Essential N-acetylglucosamine-phosphate mutase; converts GlcNAc-6-P to GlcNAc-1-P, which is a precursor for the biosynthesis of chitin and for the formation of N-glycosylated mannoproteins and glycosylphosphatidylinositol anchors[1][2][3]
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References
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- ↑ Igual JC, et al. (1997) A genetic screen reveals a role for the late G1-specific transcription factor Swi4p in diverse cellular functions including cytokinesis. J Cell Sci 110 ( Pt 14):1647-54 SGD PMID 9247198
- ↑ Hofmann M, et al. (1994) Characterization of the essential yeast gene encoding N-acetylglucosamine-phosphate mutase. Eur J Biochem 221(2):741-7 SGD PMID 8174553
- ↑ Mio T, et al. (2000) Functional cloning and mutational analysis of the human cDNA for phosphoacetylglucosamine mutase: identification of the amino acid residues essential for the catalysis. Biochim Biophys Acta 1492(2-3):369-76 SGD PMID 11004509
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