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Systematic name YEL058W
Gene name PCM1
Aliases AGM1
Feature type ORF, Verified
Coordinates Chr V:43252..44925
Primary SGDID S000000784

Description of YEL058W: Essential N-acetylglucosamine-phosphate mutase; converts GlcNAc-6-P to GlcNAc-1-P, which is a precursor for the biosynthesis of chitin and for the formation of N-glycosylated mannoproteins and glycosylphosphatidylinositol anchors[1][2][3]


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  1. Hofmann M, et al. (1994) Characterization of the essential yeast gene encoding N-acetylglucosamine-phosphate mutase. Eur J Biochem 221(2):741-7 SGD PMID 8174553
  2. Igual JC, et al. (1997) A genetic screen reveals a role for the late G1-specific transcription factor Swi4p in diverse cellular functions including cytokinesis. J Cell Sci 110 ( Pt 14)():1647-54 SGD PMID 9247198
  3. Mio T, et al. (2000) Functional cloning and mutational analysis of the human cDNA for phosphoacetylglucosamine mutase: identification of the amino acid residues essential for the catalysis. Biochim Biophys Acta 1492(2-3):369-76 SGD PMID 11004509

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