Difference between revisions of "YMR080C"
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− | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004685 YMR080C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''NAM7 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''NAM7 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr XIII:429626..426711 | |nowrap| Chr XIII:429626..426711 | ||
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+ | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004685 | ||
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− | '''Description of | + | '''Description of YMR080C:''' ATP-dependent RNA helicase of the SFI superfamily, required for nonsense mediated mRNA decay and for efficient translation termination at nonsense codons; involved in telomere maintenance<ref name='S000114270'>Askree SH, et al. (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63 {{SGDpaper|S000114270}} PMID 15161972</ref><ref name='S000061923'>de la Cruz J, et al. (1999) Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. Trends Biochem Sci 24(5):192-8 |
{{SGDpaper|S000061923}} PMID 10322435</ref> | {{SGDpaper|S000061923}} PMID 10322435</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 08:46, 27 February 2007
Share your knowledge...Edit this entry! <protect>
Systematic name | YMR080C |
Gene name | NAM7 |
Aliases | IFS2, MOF4, UPF1 |
Feature type | ORF, Verified |
Coordinates | Chr XIII:429626..426711 |
Primary SGDID | S000004685 |
Description of YMR080C: ATP-dependent RNA helicase of the SFI superfamily, required for nonsense mediated mRNA decay and for efficient translation termination at nonsense codons; involved in telomere maintenance[1][2]
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Community Commentary
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Interactions
Two Hybrid
Two Hybrid interaction with SNP1, NMD3, DBP2, NMD4, DCP2, NMD5, NMD2
Yeast Two-Hybrid screen with Upf1p as bait identified several interacting proteins [3] [4]
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References
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- ↑ Askree SH, et al. (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63 SGD PMID 15161972
- ↑ de la Cruz J, et al. (1999) Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. Trends Biochem Sci 24(5):192-8 SGD PMID 10322435
- ↑ He F and Jacobson A (1995) Identification of a novel component of the nonsense-mediated mRNA decay pathway by use of an interacting protein screen. Genes Dev 9(4):437-54 SGD PMID 7883168
- ↑ submitted by Jurgen Wittmann on 2003-04-30
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