Difference between revisions of "YGR140W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003372 YGR140W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''CBF2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''CBF2 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr VII:767434..770304 | |nowrap| Chr VII:767434..770304 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003372 | ||
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| − | '''Description of | + | '''Description of YGR140W:''' Essential kinetochore protein, component of the CBF3 multisubunit complex that binds to the CDEIII region of the centromere; Cbf2p also binds to the CDEII region possibly forming a different multimeric complex, ubiquitinated in vivo<ref name='S000074756'>Espelin CW, et al. (2003) Binding of the essential Saccharomyces cerevisiae kinetochore protein Ndc10p to CDEII. Mol Biol Cell 14(11):4557-68 {{SGDpaper|S000074756}} PMID 13679521</ref><ref name='S000054823'>Yoon HJ and Carbon J (1995) Genetic and biochemical interactions between an essential kinetochore protein, Cbf2p/Ndc10p, and the CDC34 ubiquitin-conjugating enzyme. Mol Cell Biol 15(9):4835-42 {{SGDpaper|S000054823}} PMID 7651401</ref><ref name='S000044125'>Lechner J and Carbon J (1991) A 240 kd multisubunit protein complex, CBF3, is a major component of the budding yeast centromere. Cell 64(4):717-25 |
{{SGDpaper|S000044125}} PMID 1997204</ref> | {{SGDpaper|S000044125}} PMID 1997204</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 07:46, 27 February 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YGR140W |
| Gene name | CBF2 |
| Aliases | CBF3A, CEP2, CSL5, CTF14, NDC10 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:767434..770304 |
| Primary SGDID | S000003372 |
Description of YGR140W: Essential kinetochore protein, component of the CBF3 multisubunit complex that binds to the CDEIII region of the centromere; Cbf2p also binds to the CDEII region possibly forming a different multimeric complex, ubiquitinated in vivo[1][2][3]
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Community Commentary
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Interactions
Genetic
Strain Background: A364A/S288C
Genetic interaction with MIF2
Phenotype(s): Synthetic Lethal with MIF2
at the time showed that MIF2 genetically interacts with an "established" centromere protein gene [4] [5]
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References
See Help:References on how to add references
- ↑ Espelin CW, et al. (2003) Binding of the essential Saccharomyces cerevisiae kinetochore protein Ndc10p to CDEII. Mol Biol Cell 14(11):4557-68 SGD PMID 13679521
- ↑ Yoon HJ and Carbon J (1995) Genetic and biochemical interactions between an essential kinetochore protein, Cbf2p/Ndc10p, and the CDC34 ubiquitin-conjugating enzyme. Mol Cell Biol 15(9):4835-42 SGD PMID 7651401
- ↑ Lechner J and Carbon J (1991) A 240 kd multisubunit protein complex, CBF3, is a major component of the budding yeast centromere. Cell 64(4):717-25 SGD PMID 1997204
- ↑ Meluh PB and Koshland D (1995) Evidence that the MIF2 gene of Saccharomyces cerevisiae encodes a centromere protein with homology to the mammalian centromere protein CENP-C. Mol Biol Cell 6(7):793-807 SGD PMID 7579695
- ↑ submitted by Pamela B. Meluh on 2003-03-17
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